Episode 4:
Don't you hurt my lactic bacterias! *angry nyuuuing*
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はたらく細胞!!
Episode 8:
To be honest, I find 2nd season worse, than first one.
Firstly, it lost almost all educational charm in it. First season annoyed me with constants re-introductions of the cells, but it offered quite a lot besides that. 2nd season barely explains anything, because it's more "action oriented" I guess. I think the last episode has the most comments, but most of them were already told in previous episodes, which were connected to it story-wise.
Secondly, I did not like the dynamics of the last 4 episodes. Maybe I am remembering this wrong, but I think manga had lactic bacteria and cancer cell arcs separate and they worked well as separate arcs. Here they were merged and they mangle up each other. I would prefer to see lactic bacteria for episodes 5-6 and cancer cell for episodes 7-8. Or they could just turn those into short movies even.
The only saving graces of 2nd season is that it not "real-life work conditions propaganda" as Black and lactic bacteria, that are simply too cute to hate them.